Haemolysis in Malignant Blood Diseases.

Haemolysis during Sample Preparation Alters microRNA Content of Plasma

The presence of cell-free microRNAs (miRNAs) has been detected in a range of body fluids. The miRNA content of plasma/serum in particular has been proposed as a potential source of novel biomarkers for a number of diseases. Nevertheless, the quantification of miRNAs from plasma or serum is made difficult due to inefficient isolation and lack of consensus regarding the optimal reference miRNA. T...

A Root Cause Analysis of Haemolysis Encountered in Leuco-filtration of Stored Packed Red Cells Units

Background and Aims: Leukoreduction of blood components has reduced the incidence of transfusion-associated adverse events. Leucofiltration is the most effective method of leukoreduction. We encountered haemolysis in a series of leucofiltered units. This stressed our precious inventory, added to financial loss, increased our turn-around time to issue leucofiltered blood units, and placed doubts...

A Single Radial Haemolysis Technique for Rapid Diagnosis of Goat Pox Diseases

Microangiopathic haemolytic anaemia associated with malignant haemangio-endothelioma.

A case of microangiopathic haemolytic anaemia associated with malignant haemangio-endothelioma is described. It is suggested that haemolysis may have been due to mechanical trauma sustained by the red blood cells on passage through the tumour's abnormal vasculature.

Hypertension and segmental renal hypoplasia causing a syndrome of haemolysis and uraemia.

An 11-year-old girl presented with acute renal failure and severe hypertension. The blood film showed thrombocytopenia, numerous fragmented red blood cells, and a reticulocyte count of 10%. An intravenous pyelogram showed a small contracted left kidney, and plasma renin activity was increased in the left renal vein. Treatment with minoxidil and propranolol controlled the hypertension. After nep...